There are 20 members of the Rho GTPase family in mammals; all eukaryotes have several Rho GTPases. Rho GTPases regulate cytoskeletal dynamics, cell polarity, cell migration, cell-cycle progression, ...

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The RNA world hypothesis proposes that early life was based on RNA, which subsequently devolved the storage of information to more stable DNA, and catalytic functions to more versatile proteins.

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